Info. from Dr. Nase: Please read

[prryjones]

Hi all,
I just rec'd the following information from Dr. Nase, that he wanted forwarded to the forum. He may not be posting at the moment, but he is still with us, guys. I think we should all appreciate his continued efforts and support for our behalf.
Perry

----------------------

Dr. Nase:
"I feel very excited about this cream, not only because of the theoretical benefits, but the proven clinical benefits. The main researcher behind this is Dr. Bikowski, one of the leading rosacea specialists who is a great guy and a straight shooter. If you look him up on Pubmed and type in 'Bikowski and rosacea' you will see a plethora of great journal articles by him on rosacea. "

1: Bikowski J. Related Articles, Links
Topical metronidazole combination therapy in the clinical management of rosacea.J Drugs Dermatol. 2005 Jul-Aug;4(4):473-80. Review.
PMID: 16004021 [PubMed - indexed for MEDLINE]


2: Bikowski JB. Related Articles, Links
The pharmacologic therapy of rosacea: a paradigm shift in progress.
Cutis. 2005 Mar;75(3 Suppl):27-32; discussion 33-6. Review.
PMID: 15810808 [PubMed - indexed for MEDLINE]


3: Bikowski JB, Goldman MP. Related Articles, Links
Rosacea: where are we now?
J Drugs Dermatol. 2004 May-Jun;3(3):251-61. Review.
PMID: 15176158 [PubMed - indexed for MEDLINE]


4: Bikowski JB. Related Articles, Links
Subantimicrobial dose doxycycline for acne and rosacea.
Skinmed. 2003 Jul-Aug;2(4):234-45. Review.
PMID: 14673277 [PubMed - indexed for MEDLINE]


5: Bikowski J. Related Articles, Links
The use of therapeutic moisturizers in various dermatologic disorders.
Cutis. 2001 Dec;68(5 Suppl):3-11. Review.
PMID: 11845952 [PubMed - indexed for MEDLINE]


6: Bikowski J. Related Articles, Links
The use of cleansers as therapeutic concomitants in various dermatologic disorders.
Cutis. 2001 Dec;68(5 Suppl):12-9. Review.
PMID: 11845951 [PubMed - indexed for MEDLINE]


7: Bikowski JB. Related Articles, Links
Rosacea: a tiered approach to therapy.
Cutis. 2000 Oct;66(4 Suppl):3-6. Review. No abstract available.
PMID: 11455752 [PubMed - indexed for MEDLINE]


8: Bikowski JB. Related Articles, Links
Treatment of rosacea with doxycycline monohydrate.
Cutis. 2000 Aug;66(2):149-52.
PMID: 10955198 [PubMed - indexed for MEDLINE]


Dr. Bikowski thinks this will be one of the best creams for rosacea based on his testing and designing of the cream. He has stated that it is quite common for rosacea sufferers to go through a redness, irritation or flushing period of up to 6 to 8 weeks because of the VEGF and other dilator growth factors. The 6 to 8 weeks makes sense because this is two revolutions of the epidermis. By the time the 8 weeks roles around the VEGF is not needed anymore and thus does not have vasoactive actions, the epidermis is rebuilt, thicker and stronger and the new microenvironment is now established.

I have always stuck by my guns on the warning, "Dont fight through irritation........and listen to your face", but this is one where many many go through a "bad period" until two epidermal shedding periods have taken place.

Just some food for thought.

Regards,
Geoffrey

[fut]

Is this in regards to the Neocutis cream or the Prescription Strength?

[prryjones]

Fut,
I think he is referring to the OTC.
Perry

[hozer2k]

In this case, those of us with samples should use small test spots and probably go with once a day application in order for it to last 6-8 weeks. I plan on doing this myself.

[Barbara]

Hi RedHotCanuck,

it makes me sad when I see people always demanding more in this forum. I have the feeling a lot of people take the input (time, work, patience) from Dr. Nase as granted and are even ungrateful. It’s like with most things in life. Instead of appreciating the good things we get/have and feel as very lucky and rich persons, we take them for granted and get angry if things are changing and we don’t get/have them anymore (because we feel like we are still entitled to get them).

Also every person is an individual. If Dr. Nase feels more comfortable with posting his information via another person we all should respect that. He doesn’t have to justify himself. I don’t blame him; on the contrary, I’m surprised that he is still looking for us, giving us helpful information. After all that faultfinding in the past…

I personally am focusing on harmony and appreciating the good things that I’m getting in life and don’t take them for granted. And if I meet a person in my life like Dr. Nase (with such passion, perseverance and idealism) I try to support him/her instead of always “looking for the fly in the ointment”.

All this negativity on this board recently is making me very sad.

Sorry people, I really don’t want to offend anyone with these words. They are just my thoughts.

Let us all helping each other and focusing on what is really important for us.

Take care all,
Barbara

[fut]

Hi RedHotCanuck,

it makes me sad when I see people always demanding more in this forum. I have the feeling a lot of people take the input (time, work, patience) from Dr. Nase as granted and are even ungrateful. It’s like with most things in life. Instead of appreciating the good things we get/have and feel as very lucky and rich persons, we take them for granted and get angry if things are changing and we don’t get/have them anymore (because we feel like we are still entitled to get them).

Also every person is an individual. If Dr. Nase feels more comfortable with posting his information via another person we all should respect that. He doesn’t have to justify himself. I don’t blame him; on the contrary, I’m surprised that he is still looking for us, giving us helpful information. After all that faultfinding in the past…

I personally am focusing on harmony and appreciating the good things that I’m getting in life and don’t take them for granted. And if I meet a person in my life like Dr. Nase (with such passion, perseverance and idealism) I try to support him/her instead of always “looking for the fly in the ointment”.

All this negativity on this board recently is making me very sad.

Sorry people, I really don’t want to offend anyone with these words. They are just my thoughts.

Let us all helping each other and focusing on what is really important for us.

Take care all,
Barbara

Well said. I couldn't agree more.

[scrumptious]

Oh lord lets not start bickering again

Cheers for the info prry and Dr Nase.

[Bob Bear]

Perry,

What are you personal thoughts on this treatment, as a man in the know?

I must admit, i like the sound on a super charged epidermis, but I dont like the sound of an 8 wk flushathon!

Thanks you the heads up.

BB

[fut]

Why does two epidermal cycles make sense and why will the VEGF stop at that time?

Thanks

[prryjones]

Perry,

What are you personal thoughts on this treatment, as a man in the know?

I must admit, i like the sound on a super charged epidermis, but I dont like the sound of an 8 wk flushathon!

Thanks you the heads up.

BB

Hi Bob,
I don't have a clue (I am still trying to figure this "inflammation" thing out).
Anyway, I have experienced mild redness and irritation on one cheek since beginning tx one week ago. I will give it two months.
I am also talking 20mg doxycycline (anti collagenase activity) per day, hopefully to have synergistic, or at least additve effects to the Neocutis cream.
Take care,
Perry