Just want to update people on my progress because it may help someone else. I have struggled with rosacea for years and years, since I was at least 12 years old. I have flushing, bloodshot eyes, swelling of my eyelids, nose, chin, and forehead. Then someone on this site talked about something called Histamine Intolerance. I looked it up and thought I would try a new supplement (and very expensive, unfortunately) called Histame which is supposed to help those who have trouble eating histamine rich foods. Well, guess what? My skin is not only clear but much, much less puffy. My eyes are not bloodshot but white. I look so much healthier. For me, it was Histamine Intolerance all along. That is probably why my skin and my diet were so interrelated, and why taking a mast cell inhibitor like quercetin helped me. Anyway, I am now one happy camper. I still stick to a low histamine diet, which most docs who treat Histamine Intolerance seem to recommend, but my face looks great. My whole appearance has improved. If you seem to react to high histamine foods (tomatoes, smoked fish, aged cheese, etc.) you might want to give it a whirl. Histame is very expensive, though, but I don't have much choice for myself. My body really seems to be lacking in DAO, one of the enzymes that helps the body deal with histamine.