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View Full Version : My opinion on Dapsone 5% (for acne)


todmiller
10th July 2005, 03:31 AM
Sorry to be so negative, but I just read this site:
http://www.acne.org/messageboard/lofiversion/index.php?t44949.html

and it doesn't look like dapsone is that great of a treatment. I mean, come on! When the treated subjects of the study only experience 10% greater odds of success than the vehicle!?! Are my standards too high, or is this just ridiculous? Embarrassing even!

Maybe I'm not looking at this right? What is the correct way to interpret these studies? The way I see it, there is a 30 something percent chance that this will clear any acne one might have, and the clarity is only likely to be a 2 on a scale of 0 to 4. Not trying to be negative, just logical.

When are doctors going to give us REAL treatments? You know, the kind that WORK!?! If we could get reimbursed after buying the products, and after seeing the doctors who prescribe them, every time the treatment doesn't work, maybe things would be different. But it is only a gamble for the patients! The doctors get theirs either way. So they don't care if they keep peddling the same crap, different label.

Sorry, but I'm an engineer. What happens when our design doesn't pan out? The company doesn't make money because nobody wants to buy something we make IF IT DOESN'T WORK, the program gets cancelled, we all have to find another project or another job somewhere else, and rightly so!

I hope the topical for rosacea brings better clearance than the numbers presented in this study.

todmiller
10th July 2005, 04:06 AM
Well crud, looks like I might have read the wrong article.

I don't think this URL has to do with the latest Aczone Dapsone 5% gel that was recently approved (July 7 or so) by the FDA. I'm not sure. Plus, I read the link further =), and it looks like the clearance with a longer duration study is actually quite good- in the 50+% rather than 30+%. I think I'll give this new gel a try.

Anybody know how to find clinical trial data on a drug? Is it available to the general public? I know it comes in the form of a pamphlet when you buy it. But it would be nice to review it ahead of time.

Thanks... just needed to vent I guess?