NoMoreRed!
27th June 2005, 04:48 PM
Visceral fat increases inflammatory cytokines:
Diabetes Res Clin Pract. 2005 Jul;69(1):29-35. Epub 2004 Dec 30. Related Articles, Books, LinkOut
Relationship of obesity and visceral adiposity with serum concentrations of CRP, TNF-alpha and IL-6.
Park HS, Park JY, Yu R.
Department of Family Medicine, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Pungnap-dong, Songpa-gu, Seoul 138-736, South Korea.
OBJECTIVE:: To investigate the relationship between serum concentrations of the cytokines C-reactive protein (CRP), tumor necrosis factor (TNF)-alpha, and interleukin (IL)-6, and obesity and visceral adiposity. METHODS:: A cross-sectional study of 100 Korean adults free from pre-existing inflammatory disease or cancer was performed. Body mass index (BMI), waist circumference, and serum concentrations of CRP, TNF-alpha and IL-6 were measured. In 46 obese subjects, fat mass was assessed by bioimpedance analysis and abdominal fat distribution was determined by computerized tomography scan. RESULTS:: Overall, serum concentrations of CRP, TNF-alpha and IL-6 were significantly correlated with weight, BMI, waist circumference, hip circumference, and waist-hip ratio. In obese subjects, CRP and IL-6 were significantly correlated with BMI, waist circumference and visceral adipose tissue. Multiple regression analysis showed that CRP was significantly associated with BMI, whereas IL-6 was significantly related with visceral adiposity in obese subjects. CONCLUSIONS:: The positive associations of obesity and visceral adiposity with elevated cytokine levels suggest the importance of reducing obesity and visceral adiposity to prevent elevations in cytokine levels.
CONCLUSION: If your tummy is a little bit too big (like "popping out"), you should get on a diet. In general, if you got a lot of fat on your body, you should get on a diet.
This visceral fat is dangerous. When you get a lot of it, your in a vicious cycle. The visceral fat increases inflammatory cytokines, cortisol and a lot of bad stuff. And all this bad stuff increases the visceral fat again. So, not only because of your rosacea, but also for your health, get on a diet if you are a bit too fat.
Diabetes Res Clin Pract. 2005 Jul;69(1):29-35. Epub 2004 Dec 30. Related Articles, Books, LinkOut
Relationship of obesity and visceral adiposity with serum concentrations of CRP, TNF-alpha and IL-6.
Park HS, Park JY, Yu R.
Department of Family Medicine, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Pungnap-dong, Songpa-gu, Seoul 138-736, South Korea.
OBJECTIVE:: To investigate the relationship between serum concentrations of the cytokines C-reactive protein (CRP), tumor necrosis factor (TNF)-alpha, and interleukin (IL)-6, and obesity and visceral adiposity. METHODS:: A cross-sectional study of 100 Korean adults free from pre-existing inflammatory disease or cancer was performed. Body mass index (BMI), waist circumference, and serum concentrations of CRP, TNF-alpha and IL-6 were measured. In 46 obese subjects, fat mass was assessed by bioimpedance analysis and abdominal fat distribution was determined by computerized tomography scan. RESULTS:: Overall, serum concentrations of CRP, TNF-alpha and IL-6 were significantly correlated with weight, BMI, waist circumference, hip circumference, and waist-hip ratio. In obese subjects, CRP and IL-6 were significantly correlated with BMI, waist circumference and visceral adipose tissue. Multiple regression analysis showed that CRP was significantly associated with BMI, whereas IL-6 was significantly related with visceral adiposity in obese subjects. CONCLUSIONS:: The positive associations of obesity and visceral adiposity with elevated cytokine levels suggest the importance of reducing obesity and visceral adiposity to prevent elevations in cytokine levels.
CONCLUSION: If your tummy is a little bit too big (like "popping out"), you should get on a diet. In general, if you got a lot of fat on your body, you should get on a diet.
This visceral fat is dangerous. When you get a lot of it, your in a vicious cycle. The visceral fat increases inflammatory cytokines, cortisol and a lot of bad stuff. And all this bad stuff increases the visceral fat again. So, not only because of your rosacea, but also for your health, get on a diet if you are a bit too fat.